Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 8/20 | 0.96 |
| ▸ | GRIN2A known ✓ | Q12879 | 7/20 | 0.96 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.96 |
| ▸ | ADRA2A known ✓ | P08913 | 6/20 | 0.65 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.96 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.96 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.96 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.96 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.96 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.96 |
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.96 |
| ▸ | NOS1 | P29475 | 2/20 | 0.61 |
| ▸ | NOS3 | P29474 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809224 | 0.98 | SIGMAR1 (1.00) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL78658 | 0.98 | SIGMAR1 (1.00) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL8157616 | 0.96 | SIGMAR1 (0.96) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27003083 | 0.85 | SIGMAR1 (0.76) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27003076 | 0.85 | SIGMAR1 (0.76) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27003079 | 0.85 | SIGMAR1 (0.83) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Sulfuric Acid SCHEMBL8168521 | 0.84 | SIGMAR1 (0.74) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4104665 | 0.82 | SIGMAR1 (0.71) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29970300 | 0.81 | SIGMAR1 (0.69) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27003090 | 0.81 | SIGMAR1 (0.69) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12336364-B2 | Perovskite with modified surface and method for making the same | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2025-06-17 | — | — | US | disclosed |
| CN-119968087-A | Surface modified perovskite and preparation method thereof | 香港理工大学 | 2025-05-09 | — | — | CN | disclosed |
| US-20250089431-A1 | PEROVSKITE WITH MODIFIED SURFACE AND METHOD FOR MAKING THE SAME | UNIV HONG KONG POLYTECHNIC (CN) | 2025-03-13 | — | — | US | disclosed |
| CN-117560942-A | Application of diphenyl guanidine hydrobromide serving as passivating agent in perovskite | 大连理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117560942-A | Application of diphenyl guanidine hydrobromide serving as passivating agent in perovskite | 大连理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-113165093-B | Cleaning agent composition for removing scaling powder residue | 花王株式会社 | 2024-01-02 | — | — | CN | disclosed |
| CN-113165027-B | Cleaning of flux residue | 花王株式会社 | 2023-07-07 | — | — | CN | disclosed |
| EP-4130312-A1 | FLUX AND SOLDER PASTE | Senju Metal Industry Co., Ltd. (JP) | 2023-02-08 | — | — | EP | disclosed |