SCHEMBL809224

SCHEMBL809224

N/C(=N\c1ccccc1)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 1.00
GRIN2D O15399 7/20 1.00
GRIN3B O60391 7/20 1.00
GRIN1 Q05586 7/20 1.00
GRIN2A Q12879 7/20 1.00
GRIN2B Q13224 7/20 1.00
GRIN2C Q14957 7/20 1.00
GRIN3A Q8TCU5 7/20 1.00
LMNA P02545 1/20 1.00
CYP2D6 P10635 1/20 1.00
SLC6A2 P23975 1/20 1.00
KMT2A Q03164 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
ADRA2A P08913 6/20 0.67
NOS1 P29475 1/20 0.63
ADRA2B P18089 1/20 0.56
ADRA2C P18825 1/20 0.56
HTR3E A5X5Y0 1/20 0.54
SLC22A2 O15244 1/20 0.54
SLC22A1 O15245 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78658 1.00 SIGMAR1 (1.00) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL8157616 0.98 SIGMAR1 (0.96) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Bromide SCHEMBL30258978 0.98 SIGMAR1 (0.96) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL27003076 0.87 SIGMAR1 (0.76) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL27003079 0.87 SIGMAR1 (0.83) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL27003083 0.87 SIGMAR1 (0.76) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Sulfuric Acid SCHEMBL8168521 0.86 SIGMAR1 (0.74) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4104665 0.84 SIGMAR1 (0.71) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29970300 0.82 SIGMAR1 (0.69) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL27003080 0.82 SIGMAR1 (0.69) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768807-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES Chevron Oronite Company LLC (US) 2021-01-27 EP claimed
CN-112055742-A Composition and method for preventing or reducing low speed pre-ignition in spark-ignition internal combustion engines 雪佛龙奥伦耐有限责任公司 2020-12-08 CN claimed
WO-2020194041-A2 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES CHEVRON ORONITE COMPANY LLC (US) 2020-10-01 WO claimed
WO-2019180685-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES CHEVRON ORONITE COMPANY LLC (US) 2019-09-26 WO claimed
US-20190292473-A1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES CHEVRON ORONITE COMPANY LLC 2019-09-26 US claimed
US-9944593-B2 Process for the synthesis of fluoralkyl sulfonate salts SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2018-04-17 US claimed
EP-4692247-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2026-02-11 EP disclosed
US-20260022211-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2026-01-22 US disclosed
EP-4656672-A1 METHOD FOR PRODUCING CURABLE COMPOSITION Kaneka Corporation (JP) 2025-12-03 EP disclosed
EP-4603565-A2 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES Chevron Oronite Company LLC (US) 2025-08-20 EP disclosed
EP-4105262-B1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORP (JP) 2025-04-02 EP disclosed
EP-3880771-B1 COMPOSITION AND METHOD FOR PREVENTING OR REDUCING LOW SPEED PRE-IGNITION IN SPARK-IGNITED INTERNAL COMBUSTION ENGINES CHEVRON ORONITE CO (US) 2025-03-26 EP disclosed
US-20240417559-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2024-12-19 US disclosed
US-20100004367-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-01-07 US disclosed
EP-2123720-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2009-11-25 EP disclosed
EP-2100923-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2009-09-16 EP disclosed
EP-1992665-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-19 EP disclosed
EP-1990370-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-11-12 EP disclosed
EP-1808456-A1 Rubber composition and tire Continental Aktiengesellschaft (DE) 2007-07-18 EP disclosed
EP-0330151-A2 Bag for the storage of blood platelets NISSHO CORPORATION (JP) 1989-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022211-A1 CURABLE COMPOSITION H1-4, H1-0, H1-2 SIGMAR1 837/4885GRIN2D 1604/4885GRIN3B 1996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.