Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 9/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112483 | 0.84 | TRPC6 (0.43) | IRAK4MKNK1MKNK2GSK3BGABRP | |
| SCHEMBL22834515 | 0.84 | TRPC6 (0.43) | IRAK4MKNK1MKNK2GSK3BGABRP | |
| SCHEMBL22834964 | 0.84 | GABRP (0.41) | IRAK4MKNK1MKNK2GSK3BGABRP | |
| SCHEMBL22834979 | 0.83 | MKNK1 (0.47) | IRAK4MKNK1MKNK2GSK3BGABRP | |
| Hydrochloric Acid SCHEMBL22834993 | 0.83 | GABRP (0.41) | IRAK4MKNK1MKNK2GSK3BGABRP | |
| SCHEMBL22235215 | 0.75 | ALOX5AP (0.40) | TRPC6 | |
| SCHEMBL5036812 | 0.75 | IRAK4 (0.66) | IRAK4MKNK1MKNK2PARP10 | |
| SCHEMBL22234714 | 0.73 | ALOX5AP (0.38) | TRPC6 | |
| SCHEMBL31208535 | 0.72 | IRAK4 (0.60) | IRAK4MKNK1MKNK2GSK3BPARP10 | |
| SCHEMBL17846624 | 0.72 | IRAK4 (0.60) | IRAK4MKNK1MKNK2GSK3BPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230087118-A1 | IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230087118-A1 | IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | IRAK4, IRAK2, IRAK1 | IRAK4 1/4885MKNK1 667/4885MKNK2 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.