SCHEMBL30260486

SCHEMBL30260486

O=C1c2cccc([N+](=O)[O-])c2C(=O)C1(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 1.00
CA2 P00918 9/20 1.00
CA7 P43166 9/20 1.00
CA9 Q16790 9/20 1.00
S100A4 P26447 2/20 0.58
PTPRC P08575 1/20 0.53
RECQL P46063 2/20 0.51
MAPT P10636 2/20 0.51
KMT2A Q03164 1/20 0.51
MCL1 Q07820 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
MAPK1 P28482 1/20 0.48
CASP1 P29466 1/20 0.48
BACE1 P56817 1/20 0.48
EHMT2 Q96KQ7 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GPR35 Q9HC97 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8665512 1.00 CA1 (1.00) CA1CA2CA7CA9S100A4
SCHEMBL28285608 0.74 CA1 (0.67) CA1CA2CA7CA9PTPRC
SCHEMBL2347136 0.74 S100A4 (0.84) CA1CA2CA7CA9S100A4
SCHEMBL28651375 0.74 S100A4 (0.92) CA1CA2CA7CA9S100A4
SCHEMBL9257330 0.74 S100A4 (0.77) CA1CA2CA7CA9S100A4
SCHEMBL2599501 0.74 S100A4 (1.00) CA1CA2CA7CA9S100A4
Silver SCHEMBL29163240 0.74 CA1 (0.74) CA1CA2CA7CA9RECQL
SCHEMBL7625099 0.73 S100A4 (0.63) CA1CA2CA7CA9S100A4
SCHEMBL30408893 0.73 S100A4 (0.63) CA1CA2CA7CA9S100A4
SCHEMBL3039191 0.72 TDP1 (0.67) CA1CA2CA7CA9S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010912-A Antiviral 1, 3-dioxoindene compounds 诺华股份有限公司 2026-05-12 CN disclosed
CN-115916763-B Antiviral 1, 3-dioxoindene compounds 诺华股份有限公司 2025-06-03 CN disclosed
CN-115867545-A Antiviral 1,3 dioxoindene compounds 诺华股份有限公司 2023-03-28 CN disclosed
EP-4139301-A1 ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS Novartis AG (CH) 2023-03-01 EP disclosed
EP-4139290-A1 ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS Novartis AG (CH) 2023-03-01 EP disclosed