Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 1.00 |
| ▸ | PTPRB | P23467 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.89 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.89 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.89 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23483908 | 1.00 | PTPRA (1.00) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| SCHEMBL29470816 | 1.00 | PTPRA (1.00) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| SCHEMBL27337933 | 1.00 | PTPRA (1.00) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| Nitric Acid SCHEMBL30472695 | 0.94 | HIF1A (1.00) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| SCHEMBL15087108 | 0.92 | PTPRA (0.84) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| SCHEMBL25016361 | 0.81 | PTPRA (0.69) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| SCHEMBL14679079 | 0.80 | PTPRA (0.66) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| SCHEMBL1068031 | 0.76 | PTPRA (0.61) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| SCHEMBL1068034 | 0.76 | PTPRA (0.61) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 | |
| Leucine SCHEMBL3275050 | 0.75 | PTPRA (0.60) | PTPRAPTPRBHIF1AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230044407-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | THE TRUSTEES OF DARTMOUTH COLLEGE | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230044407-A1 | TARGETING MB2 OF THE MYC ONCOGENE AND ITS INTERACTION WITH TRRAP IN CANCER | MYCBP, MYC, TERF2IP | PTPRA 1048/4885PTPRB 951/4885HIF1A 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.