Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.66 |
| ▸ | PTPRB | P23467 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10327168 | 0.86 | PTPRA (0.50) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25016361 | 0.85 | PTPRA (0.69) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27337933 | 0.80 | PTPRA (1.00) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29470816 | 0.80 | PTPRA (1.00) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23483908 | 0.80 | PTPRA (1.00) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL30260573 | 0.80 | PTPRA (1.00) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2609273 | 0.79 | MEN1 (0.62) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3275224 | 0.76 | KMT2A (0.62) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14679071 | 0.75 | PTPRA (0.57) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| Nitric Acid SCHEMBL30472695 | 0.75 | HIF1A (1.00) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8367822-B2 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367822-B2 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | LRP6, BMP6, WNT3A | PTPRA 923/4885PTPRB 888/4885ALDH1A1 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.