Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.61 |
| ▸ | PTPRB | P23467 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 3/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068031 | 1.00 | PTPRA (0.61) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16971289 | 0.84 | PTPRA (0.55) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16971288 | 0.84 | PTPRA (0.55) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7420912 | 0.83 | ITGB1 (0.68) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7420913 | 0.83 | ITGB1 (0.68) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2307975 | 0.81 | PTPRA (0.58) | PTPRAPTPRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL507169 | 0.80 | KDM4E (0.77) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL22455572 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14338225 | 0.78 | SMN1; SMN2 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10227852 | 0.78 | SMN1; SMN2 (0.68) | ALDH1A1CYP1A2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170370916-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-12-28 | — | — | US | disclosed |
| US-20150369800-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-12-24 | — | — | US | disclosed |
| US-8940506-B2 | High-sensitive fluorescent energy transfer assay using fluoresent amino acids and fluorescent proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-01-27 | — | — | US | disclosed |
| US-20110117556-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-05-19 | — | — | US | disclosed |
| EP-2271662-A2 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | The Regents Of The University Of California (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009117726-A2 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-09-24 | — | — | WO | disclosed |
| US-20070161807-A1 | Method for manufacturing optically pure coumaryl amino acids and the novel coumaryl aminoacids thus obtained | INSERM (INSTITUT NATIONAL DE LA SANT'E ET DE LA RECHERCHE MEDICALE (FR) | 2007-07-12 | — | — | US | disclosed |
| EP-1711483-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACID SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005075448-A2 | A METHOD FOR MANUFACTURING OPTICALLY PURE COUMARYL AMINO ACIDS SALTS AND THE COUMARYL AMINO ACID SALTS THUS OBTAINED | INSTITUT NATIONAL DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-08-18 | — | — | WO | disclosed |
| EP-1559712-A1 | A method for manufacturing optically active coumaryl amino acid salts and the coumaryl aminoacid salts thus obtained | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161807-A1 | Method for manufacturing optically pure coumaryl amino acids and the novel coumaryl aminoacids thus obtained | CRYAA, BCAT2, BCAT1 | PTPRA 3082/4885PTPRB 3029/4885ALDH1A1 874/4885 |
| US-20110117556-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | SLC7A1, SARS1, GFPT1 | PTPRA 2520/4885PTPRB 2280/4885ALDH1A1 4338/4885 |
| US-20150369800-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS | GFPT1, PHAX, TARBP1 | PTPRA 2396/4885PTPRB 2091/4885ALDH1A1 4301/4885 |
| US-20170370916-A1 | HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESCENT PROTEINS | ACP1, BCAT1, SARS1 | PTPRA 2113/4885PTPRB 2135/4885ALDH1A1 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.