SCHEMBL30262192

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C

nearest known ligand 0.67

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	10/20	0.67

▸	ECE1	P42892	1/20	0.67

▸	MUS81	Q96NY9	1/20	0.67

▸	IL23R	Q5VWK5	2/20	0.66

▸	NR3C1	P04150	4/20	0.65

▸	PTH1R	Q03431	3/20	0.65

▸	GCGR	P47871	1/20	0.64

▸	GIPR	P48546	1/20	0.64

▸	KISS1R	Q969F8	1/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29695609	0.93	NR3C1 (0.69)	GLP1RECE1MUS81IL23RNR3C1
SCHEMBL31656511	0.91	IL23R (0.70)	GLP1RECE1MUS81IL23RNR3C1
SCHEMBL31378965	0.91	GLP1R (0.71)	GLP1RECE1MUS81IL23R
SCHEMBL30567741	0.91	NR3C1 (0.72)	GLP1RECE1MUS81IL23RNR3C1
SCHEMBL30648468	0.91	GLP1R (0.72)	GLP1RECE1MUS81IL23RNR3C1
SCHEMBL30065622	0.91	GLP1R (0.69)	GLP1RECE1MUS81IL23RPTH1R
SCHEMBL30433545	0.90	GLP1R (0.71)	GLP1RECE1MUS81NR3C1GCGR
SCHEMBL30512502	0.90	PTH1R (0.63)	GLP1RECE1MUS81IL23RPTH1R
SCHEMBL30648483	0.90	GLP1R (0.71)	GLP1RECE1MUS81IL23RNR3C1
SCHEMBL30567750	0.89	NR3C1 (0.71)	GLP1RECE1MUS81IL23RNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230040544-A1	COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)	SAREPTA THERAPEUTICS, INC.	2023-02-09	—	—	US	disclosed