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Sugi Predict / Compounds / SCHEMBL30567741

SCHEMBL30567741

SCHEMBL30567741

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)O)C(C)C)C(C)C)[C@@H](C)O

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 4/20 0.72
▸ GLP1R P43220 10/20 0.71
▸ ECE1 P42892 1/20 0.71
▸ MUS81 Q96NY9 1/20 0.71
▸ IL23R Q5VWK5 6/20 0.68
▸ GCGR P47871 1/20 0.68
▸ GIPR P48546 1/20 0.68
▸ CCKBR P32239 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31656511 0.96 IL23R (0.70) NR3C1GLP1RECE1MUS81IL23R
SCHEMBL30567691 0.96 IL23R (0.70) NR3C1GLP1RECE1MUS81IL23R
SCHEMBL30567750 0.94 NR3C1 (0.71) NR3C1GLP1RECE1MUS81IL23R
SCHEMBL30433545 0.94 GLP1R (0.71) NR3C1GLP1RECE1MUS81GCGR
SCHEMBL30648468 0.94 GLP1R (0.72) NR3C1GLP1RECE1MUS81IL23R
SCHEMBL29695609 0.94 NR3C1 (0.69) NR3C1GLP1RECE1MUS81IL23R
SCHEMBL30648483 0.93 GLP1R (0.71) NR3C1GLP1RECE1MUS81IL23R
SCHEMBL30567742 0.92 GLP1R (0.73) GLP1RGCGR
SCHEMBL29913332 0.92 GLP1R (0.74) GLP1RECE1MUS81IL23RCCKBR
SCHEMBL31694515 0.92 IL23R (0.75) NR3C1GLP1RECE1MUS81IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NR3C1 914/4885GLP1R 2288/4885ECE1 3688/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NR3C1 914/4885GLP1R 2288/4885ECE1 3688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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