Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 16/20 | 0.76 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522401 | 0.91 | NOTUM (0.67) | NOTUMDPP4CYP3A4ALDH1A1 | |
| SCHEMBL22491869 | 0.87 | NOTUM (0.59) | NOTUMALDH1A1 | |
| SCHEMBL30656765 | 0.87 | NOTUM (0.59) | NOTUMALDH1A1 | |
| SCHEMBL22655697 | 0.87 | NOTUM (0.59) | NOTUMALDH1A1 | |
| SCHEMBL16695509 | 0.87 | NOTUM (1.00) | NOTUM | |
| SCHEMBL16695070 | 0.83 | NOTUM (0.74) | NOTUMCYP3A4ALDH1A1 | |
| SCHEMBL16695087 | 0.83 | NOTUM (0.74) | NOTUMCYP3A4ALDH1A1 | |
| SCHEMBL16695071 | 0.83 | NOTUM (0.74) | NOTUMCYP3A4ALDH1A1 | |
| SCHEMBL16695098 | 0.83 | NOTUM (0.54) | NOTUMCYP3A4ALDH1A1 | |
| SCHEMBL16695131 | 0.83 | NOTUM (0.54) | NOTUMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | CYP3A7, CYP51A1, NT5C3B | NOTUM 473/4885DPP4 3065/4885CYP3A4 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.