Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | EIF4E | P06730 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 2/20 | 0.42 |
| ▸ | ATP4B | P51164 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263390 | 0.86 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263223 | 0.79 | KDM4E (0.51) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263241 | 0.79 | KDM4E (0.47) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263292 | 0.78 | CYP1A1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263192 | 0.77 | CYP1A1 (0.52) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263309 | 0.76 | NNMT (0.40) | CYP1A2EIF4EKMT2AALDH1A1 | |
| SCHEMBL30263328 | 0.73 | CYP19A1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263291 | 0.72 | KDM4E (0.50) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263347 | 0.72 | CYP19A1 (0.63) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL30263305 | 0.70 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |