SCHEMBL30263284

SCHEMBL30263284

COCc1ccccc1-c1csc(-c2cc(N3CCN(S(C)(=O)=O)CC3)cnc2C(N)=O)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.35
TTK P33981 3/20 0.35
CDC25A P30304 1/20 0.34
CDC25B P30305 1/20 0.34
CDC25C P30307 1/20 0.34
DUSP3 P51452 1/20 0.34
MAPT P10636 2/20 0.34
SYK P43405 3/20 0.34
AOC3 Q16853 2/20 0.34
RORC P51449 1/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
JAK3 P52333 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SUV39H2 Q9H5I1 1/20 0.33
PDE1B Q01064 1/20 0.33
AXL P30530 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30263317 0.91 SUV39H2 (0.36) TTKMAPTSYKRORCJAK2
SCHEMBL30292577 0.86 HSD17B10 (0.36) TTKMAPTSYKRORCJAK2
SCHEMBL30263306 0.86 CYP1A1 (0.41) MAPTALDH1A1HPGDAXL
SCHEMBL30263208 0.84 EIF4E (0.35) TTKSYKRORCJAK2JAK1
SCHEMBL30263330 0.78 ABL1 (0.38) MAPTSYKJAK2JAK1JAK3
SCHEMBL24107461 0.77 MAPT (0.41) MAPTRORCALDH1A1HPGDALOX15
SCHEMBL30263175 0.77 MAPT (0.41) MAPTRORCALDH1A1HPGDALOX15
SCHEMBL30263316 0.76 EIF4E (0.45)
SCHEMBL30263261 0.74 CYP1A1 (0.46) MAPTALDH1A1HPGD
SCHEMBL30292498 0.72 KDM4E (0.42) MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed
CN-115916776-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2023-04-04 CN disclosed