Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 2/20 | 0.38 |
| ▸ | ATP4B | P51164 | 2/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 3/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263259 | 0.88 | CYP19A1 (0.48) | CYP19A1C1SCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL30263223 | 0.79 | KDM4E (0.51) | CYP19A1C1SCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL30263257 | 0.79 | EIF4E (0.46) | CYP19A1C1SEIF4ENPC1RAB9A | |
| SCHEMBL30263311 | 0.77 | JAK2 (0.48) | CYP1A1CYP1A2CYP1B1KDM4E | |
| SCHEMBL30292519 | 0.71 | CHEK2 (0.38) | C1SEIF4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29695142 | 0.71 | PARP1 (0.53) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24107419 | 0.71 | KDM4E (0.52) | KDM4EATP4AATP4BHPGDSNPC1 | |
| SCHEMBL30263180 | 0.69 | PARP1 (0.40) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22728617 | 0.68 | LMNA (0.59) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23835432 | 0.68 | LMNA (0.67) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-115916776-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2023-04-04 | — | — | CN | disclosed |