Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 2/20 | 0.44 |
| ▸ | ATP4B | P51164 | 2/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 2/20 | 0.43 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263307 | 0.88 | CYP19A1 (0.42) | CYP19A1NPC1RAB9ASMN1; SMN2ATP4A | |
| SCHEMBL30263311 | 0.81 | JAK2 (0.48) | HTTMEN1MAPTKMT2ACYP1A1 | |
| SCHEMBL23835432 | 0.77 | LMNA (0.67) | SMN1; SMN2HTTMEN1NR1I2LMNA | |
| SCHEMBL5968562 | 0.74 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2C1SEIF4E | |
| SCHEMBL22728617 | 0.74 | LMNA (0.59) | NPC1RAB9ASMN1; SMN2HTTMEN1 | |
| SCHEMBL20333484 | 0.74 | NPC1 (0.62) | CYP19A1NPC1RAB9ASMN1; SMN2EIF4E | |
| SCHEMBL30263367 | 0.74 | CYP19A1 (0.57) | CYP19A1NPC1RAB9ASMN1; SMN2EIF4E | |
| SCHEMBL27965806 | 0.73 | RAB9A (0.78) | CYP19A1NPC1RAB9ASMN1; SMN2EIF4E | |
| SCHEMBL28730343 | 0.73 | LMNA (0.64) | NPC1RAB9ASMN1; SMN2HTTMEN1 | |
| SCHEMBL30263274 | 0.72 | ADORA3 (0.65) | NPC1RAB9ASMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |