SCHEMBL30263308

SCHEMBL30263308

Cn1cc(-c2csc(-c3ccccc3C(N)=O)n2)cn1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C1S P09871 2/20 0.51
EIF4E P06730 1/20 0.48
PIK3CD O00329 1/20 0.48
PDK2 Q15119 1/20 0.47
GRM2 Q14416 1/20 0.46
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
LCK P06239 1/20 0.43
BTK Q06187 1/20 0.43
BCAT2 O15382 1/20 0.42
IRAK4 Q9NWZ3 2/20 0.41
SMARCA2 P51531 1/20 0.41
SMARCA4 P51532 1/20 0.41
CCNC P24863 1/20 0.41
CDK8 P49336 1/20 0.41
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
CHEK1 O14757 1/20 0.40
HSP90AA1 P07900 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965134 0.85 PIK3CD (0.59) PIK3CDPDK2GRM2LCKBTK
SCHEMBL21724955 0.85 PIK3CD (0.59) PIK3CDPDK2GRM2LCKBTK
SCHEMBL30263228 0.84 CAPN1 (0.46) C1SPIK3CDIRAK4HSP90AA1TGFBR1
SCHEMBL5968562 0.81 RAB9A (0.62) C1SEIF4ERAB9ASMN1; SMN2NPC1
SCHEMBL30263279 0.78 C1S (0.45) C1SPDK2MKNK1MKNK2
SCHEMBL30263343 0.78 CYP19A1 (0.63) EIF4ERAB9ASMN1; SMN2NPC1MKNK1
SCHEMBL27965806 0.74 RAB9A (0.78) EIF4ERAB9ASMN1; SMN2NPC1BCAT2
SCHEMBL16179380 0.73 BTK (0.55) PIK3CDPDK2GRM2LCKBTK
SCHEMBL19484795 0.72 BRD4 (0.51) PIK3CDPDK2GRM2LCKBTK
SCHEMBL31048540 0.72 PDK2 (0.55) PIK3CDPDK2GRM2LCKBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed