Amanozine

Amanozine

SCHEMBL30264199

Nc1ncnc(Nc2ccccc2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL6 P41182 3/20 1.00
RAB9A P51151 3/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
ADORA3 P0DMS8 1/20 0.69
SLC6A2 P23975 1/20 0.69
PDE4A P27815 1/20 0.69
KDR P35968 1/20 0.69
KDM4E B2RXH2 3/20 0.60
HTT P42858 2/20 0.60
MAPT P10636 4/20 0.59
GAA P10253 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
KCNH2 Q12809 1/20 0.58
SCN5A Q14524 1/20 0.58
SCN9A Q15858 1/20 0.58
MAPK1 P28482 2/20 0.54
ROCK1 Q13464 1/20 0.53
LMNA P02545 1/20 0.53
NPC1 O15118 2/20 0.51
KMT2A Q03164 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amanozine SCHEMBL689928 1.00 BCL6 (1.00) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
Amanozine SCHEMBL2490900 0.98 BCL6 (0.96) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
Amanozine SCHEMBL27930031 0.95 BCL6 (0.90) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
SCHEMBL824411 0.86 BCL6 (0.74) BCL6RAB9ASMN1; SMN2KDRKDM4E
SCHEMBL21496119 0.85 SMN1; SMN2 (0.74) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
SCHEMBL14972606 0.83 BCL6 (0.71) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
SCHEMBL21496108 0.82 BCL6 (0.70) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
Chlorazanil SCHEMBL180422 0.81 ADORA3 (1.00) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
Chlorazanil SCHEMBL29652081 0.81 ADORA3 (1.00) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2
SCHEMBL8236544 0.81 SMN1; SMN2 (1.00) BCL6RAB9ASMN1; SMN2ADORA3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819363-B Ketone amide compound and preparation method and application thereof 浙江工业大学 2025-04-01 CN disclosed
CN-115819363-A Ketone amide compound and preparation method and application thereof 浙江工业大学 2023-03-21 CN disclosed