Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.69 |
| ▸ | KDR | P35968 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amanozine SCHEMBL30264199 | 1.00 | BCL6 (1.00) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| Amanozine SCHEMBL2490900 | 0.98 | BCL6 (0.96) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| Amanozine SCHEMBL27930031 | 0.95 | BCL6 (0.90) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| SCHEMBL824411 | 0.86 | BCL6 (0.74) | BCL6RAB9ASMN1; SMN2KDRKDM4E | |
| SCHEMBL21496119 | 0.85 | SMN1; SMN2 (0.74) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| SCHEMBL14972606 | 0.83 | BCL6 (0.71) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| SCHEMBL21496108 | 0.82 | BCL6 (0.70) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| Chlorazanil SCHEMBL180422 | 0.81 | ADORA3 (1.00) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| Chlorazanil SCHEMBL29652081 | 0.81 | ADORA3 (1.00) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 | |
| SCHEMBL8236544 | 0.81 | SMN1; SMN2 (1.00) | BCL6RAB9ASMN1; SMN2ADORA3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 531 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183932-A2 | MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | claimed |
| EP-3485908-B1 | THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS | MEREO BIOPHARMA 5 INC (US) | 2021-08-18 | — | — | EP | claimed |
| EP-3072526-B1 | THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS | ONCOMED PHARM INC (US) | 2018-09-26 | — | — | EP | claimed |
| US-9982042-B2 | Therapeutic combination and methods of treatment with a DLL4 antagonist and an anti-hypertensive agent | ONCOMED PHARMACEUTICALS, INC. (US) | 2018-05-29 | — | — | US | claimed |
| US-20170166632-A1 | Therapeutic Combination and Methods of Treatment With A DLL4 Antagonist and an Anti-Hypertensive Agent | ONCOMED PHARMACEUTICALS, INC. | 2017-06-15 | — | — | US | claimed |
| US-9511139-B2 | Therapeutic combination and methods of treatment with a DLL4 antagonist and an anti-hypertensive agent | ONCOMED PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | claimed |
| EP-3072526-A1 | THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS | Oncomed Pharmaceuticals, Inc. (US) | 2016-09-28 | — | — | EP | claimed |
| EP-2488204-B1 | THERAPEUTIC COMBINATION AND USE OF DLL4 ANTAGONIST ANTIBODIES AND ANTI-HYPERTENSIVE AGENTS | ONCOMED PHARM INC (US) | 2016-04-06 | — | — | EP | claimed |
| US-20150118232-A1 | Therapeutic Combination and Methods of Treatment With A DLL4 Antagonist and an Anti-Hypertensive Agent | ONCOMED PHARMACEUTICALS, INC. | 2015-04-30 | — | — | US | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-1165526-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZINES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| CN-1315945-A | Nitrate salts of antihypertensive drugs | NICOX SA (FR) | 2001-10-03 | — | — | CN | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1087953-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 2001-04-04 | — | — | EP | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000061567-A1 | METHOD FOR PREPARING SUBSTITUTED TRIAZINES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-10-19 | — | — | WO | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| WO-1999067231-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 1999-12-29 | — | — | WO | claimed |
| US-5990310-A | REACTING A PHENYLAZOANILINE WITH A CYANURIC HALIDE AND REDUCING THE PHENYLAZOPHENYLAMINO-S-TRIAZINE TO PRODUCE AN AMINOANILINO-S-TRIAZINE FOLLOWED BY ALKYLATION; OZONE RESISTANCE; ANTISOILANTS; DISCOLORATION INHIBITION | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-11-23 | — | — | US | claimed |
| US-4526835-A | Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure | HITACHI, LTD. (JP) | 1985-07-02 | — | — | US | claimed |