SCHEMBL30264355

SCHEMBL30264355

NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.45
REN P00797 2/20 0.40
ACE P12821 1/20 0.40
CMA1 P23946 2/20 0.40
XIAP P98170 1/20 0.40
ITGB1 P05556 2/20 0.38
ITGA5 P08648 1/20 0.38
NMUR2 Q9GZQ4 2/20 0.38
NMUR1 Q9HB89 2/20 0.38
F2 P00734 2/20 0.38
ITGA4 P13612 1/20 0.37
F10 P00742 1/20 0.37
PRSS1 P07477 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30353032 0.93 F2 (0.42) OPRM1NMUR2NMUR1F2F10
SCHEMBL29591889 0.91 OPRM1 (0.46) OPRM1NMUR2NMUR1F2
SCHEMBL29679979 0.89 CAPN1 (0.48) XIAPNMUR2NMUR1
SCHEMBL29660884 0.87 CAPN1 (0.47) OPRM1RENACECMA1XIAP
SCHEMBL30315472 0.85 XIAP (0.52) OPRM1RENACEXIAP
SCHEMBL30315374 0.85 REN (0.51) RENACEF2
SCHEMBL28313317 0.85 ACE (0.48) RENACEF2
SCHEMBL28313314 0.85 ACE (0.48) RENACEF2
SCHEMBL30264441 0.85 OPRM1 (0.42) OPRM1RENACECMA1XIAP
SCHEMBL29641641 0.84 OPRM1 (0.51) OPRM1RENACECMA1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321218-A1 SARS-COV2 CORONAVIRUS RECONSTITUTED RBM AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-10-12 US disclosed
US-11746127-B2 Coronaviruses epitope-based vaccines RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-09-05 US disclosed
EP-4132949-A1 SARS-COV2 CORONAVIRUS RECONSTITUTED RBM AND USES THEREOF Ramot at Tel-Aviv University Ltd. (IL) 2023-02-15 EP disclosed