SCHEMBL30264590

SCHEMBL30264590

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 1/20 0.47
▸ QRFPR Q96P65 1/20 0.43
▸ NPY4R P50391 9/20 0.43
▸ NPY5R Q15761 8/20 0.43
▸ NPY1R P25929 7/20 0.43
▸ NPY2R P49146 5/20 0.43
▸ MC4R P32245 2/20 0.41
▸ C5AR1 P21730 1/20 0.40
▸ PTGER4 P35408 1/20 0.40
▸ FNTA P49354 1/20 0.40
▸ FNTB P49356 1/20 0.40
▸ PGGT1B P53609 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31412180 0.95 QRFPR (0.45) APLNRQRFPRNPY4RNPY5RNPY1R
SCHEMBL29670693 0.94 SLC15A2 (0.43) APLNRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30264577 0.92 MC4R (0.52) MC4RC5AR1
SCHEMBL29605732 0.92 QRFPR (0.48) APLNRQRFPRNPY4RNPY5RNPY1R
SCHEMBL30045207 0.91 FNTA (0.47) APLNRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30264773 0.91 APLNR (0.47) APLNRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30264630 0.90 FNTA (0.46) APLNRQRFPRNPY4RNPY5RNPY1R
SCHEMBL30264635 0.89 NPY4R (0.51) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30264553 0.89 APLNR (0.45) APLNRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30182954 0.89 NPY4R (0.42) APLNRNPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R APLNR 58/4885QRFPR 60/4885NPY4R 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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