Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | IL23R | Q5VWK5 | 6/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30037495 | 0.93 | MC4R (0.52) | MC4RGHSRC5AR1IL23RKISS1R | |
| SCHEMBL31555126 | 0.93 | MC4R (0.49) | MC4RGHSRC5AR1KISS1R | |
| SCHEMBL30264785 | 0.93 | GHSR (0.55) | MC4RGHSRIL23RKISS1R | |
| SCHEMBL30264726 | 0.92 | GHSR (0.53) | MC4RGHSRC5AR1KISS1R | |
| SCHEMBL29476431 | 0.92 | GHSR (0.53) | MC4RGHSRC5AR1KISS1R | |
| SCHEMBL29476499 | 0.92 | MC4R (0.50) | MC4RGHSRC5AR1KISS1R | |
| SCHEMBL30264590 | 0.92 | APLNR (0.47) | MC4RC5AR1 | |
| SCHEMBL30264772 | 0.92 | C5AR1 (0.51) | MC4RC5AR1IL23RKISS1RCTSL | |
| SCHEMBL30264941 | 0.91 | MC4R (0.49) | MC4RGHSRC5AR1IL23RKISS1R | |
| SCHEMBL29476562 | 0.91 | MC4R (0.50) | MC4RGHSRC5AR1KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240391954-A1 | MC4R AGONIST PEPTIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-11-28 | — | — | US | disclosed |
| EP-4392072-A1 | MC4R AGONIST PEPTIDES | The Regents Of The University Of Michigan (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028538-A1 | MC4R AGONIST PEPTIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240391954-A1 | MC4R AGONIST PEPTIDES | MC4R, MC3R, MC5R | MC4R 1/4885GHSR 24/4885C5AR1 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.