SCHEMBL30264847

SCHEMBL30264847

C[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(Br)CNC(=N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 14/20 0.53
▸ NPBWR1 P48145 2/20 0.49
▸ IL23R Q5VWK5 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264989 1.00 KISS1R (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264787 1.00 KISS1R (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264873 1.00 KISS1R (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264951 1.00 KISS1R (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264606 1.00 KISS1R (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264982 0.99 KISS1R (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264881 0.99 KISS1R (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264531 0.98 KISS1R (0.52) KISS1RNPBWR1IL23R
SCHEMBL30264968 0.96 NPBWR1 (0.53) KISS1RNPBWR1IL23R
SCHEMBL30264987 0.95 IL23R (0.53) KISS1RNPBWR1IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R KISS1R 72/4885NPBWR1 29/4885IL23R 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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