SCHEMBL30264856

SCHEMBL30264856

C[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(Br)CNC(=N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CXCR4 P61073 9/20 0.55
▸ IL23R Q5VWK5 1/20 0.52
▸ C5AR1 P21730 1/20 0.52
▸ OPRM1 P35372 6/20 0.50
▸ OPRK1 P41145 6/20 0.50
▸ NPBWR1 P48145 1/20 0.49
▸ KISS1R Q969F8 1/20 0.49
▸ MC4R P32245 1/20 0.48
▸ MC5R P33032 1/20 0.48
▸ MC3R P41968 1/20 0.48
▸ MC1R Q01726 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264768 0.94 IL23R (0.57) CXCR4IL23RC5AR1OPRM1OPRK1
SCHEMBL29511552 0.91 CXCR4 (0.57) CXCR4IL23RC5AR1OPRM1OPRK1
SCHEMBL30264968 0.89 NPBWR1 (0.53) IL23RNPBWR1KISS1R
SCHEMBL30264798 0.88 KISS1R (0.52) CXCR4IL23RC5AR1KISS1R
SCHEMBL30264942 0.88 KISS1R (0.52) CXCR4IL23RC5AR1KISS1R
SCHEMBL31452905 0.88 CXCR4 (0.62) CXCR4IL23RC5AR1OPRM1OPRK1
SCHEMBL30264873 0.86 KISS1R (0.53) IL23RNPBWR1KISS1R
SCHEMBL30264606 0.86 KISS1R (0.53) IL23RNPBWR1KISS1R
SCHEMBL30264787 0.86 KISS1R (0.53) IL23RNPBWR1KISS1R
SCHEMBL30264982 0.86 KISS1R (0.53) IL23RNPBWR1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R CXCR4 1454/4885IL23R 359/4885C5AR1 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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