SCHEMBL30265201

SCHEMBL30265201

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nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 1/20 0.53
▸ MAGI3 Q5TCQ9 1/20 0.52
▸ CCKBR P32239 3/20 0.50
▸ CCKAR P32238 1/20 0.49
▸ IL23R Q5VWK5 10/20 0.49
▸ RXFP1 Q9HBX9 1/20 0.47
▸ GRPR P30550 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31247979 0.96 CCKBR (0.53) PRMT1MAGI3CCKBRIL23RRXFP1
SCHEMBL30342394 0.94 MAGI3 (0.54) PRMT1MAGI3CCKBRCCKARIL23R
SCHEMBL29939669 0.90 PRMT1 (0.58) PRMT1MAGI3CCKBRCCKARIL23R
SCHEMBL31018602 0.89 MAGI3 (0.56) PRMT1MAGI3CCKBRIL23RRXFP1
SCHEMBL30903449 0.86 OPRD1 (0.53) PRMT1MAGI3CCKBRCCKAR
SCHEMBL31442335 0.84 MAGI3 (0.56) PRMT1MAGI3CCKBRCCKARIL23R
SCHEMBL30692610 0.82 IL23R (0.59) CCKBRCCKARIL23RGRPR
SCHEMBL30810352 0.82 PRMT1 (0.57) PRMT1CCKBRCCKARGRPR
SCHEMBL30051843 0.82 ACE (0.56) —
SCHEMBL30051924 0.82 ACE (0.59) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218042-A1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI (FR) 2024-07-04 — — US disclosed
EP-4392440-A2 COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS River 2 Renal Corp. (US) 2024-07-03 — — EP disclosed
US-11725036-B2 Modified lipidated relaxin B chain peptides and their therapeutic use SANOFI (FR) 2023-08-15 — — US disclosed
WO-2023028008-A2 COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS RIVER 2 RENAL CORP. (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218042-A1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE RXFP1, RXFP2, RXFP4 PRMT1 562/4885MAGI3 2402/4885CCKBR 104/4885
US-11725036-B2 Modified lipidated relaxin B chain peptides and their therapeutic use SCTR, RXFP1, RXFP3 PRMT1 2161/4885MAGI3 3680/4885CCKBR 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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