Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31001726 | 1.00 | DRD2 (0.35) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL19972697 | 1.00 | DRD2 (0.35) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL19972433 | 1.00 | DRD2 (0.35) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL19972580 | 1.00 | DRD2 (0.35) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL31001669 | 1.00 | DRD2 (0.35) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL30524057 | 0.93 | HTR1A (0.33) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL30265695 | 0.93 | HTR1A (0.33) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL19972428 | 0.93 | HTR1A (0.33) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL19972429 | 0.93 | HTR1A (0.33) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 | |
| SCHEMBL19972707 | 0.93 | HTR1A (0.33) | DRD2HCRTR1HCRTR2PTGDR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359610-A | MENIN-MLL interaction inhibitors | 生命医药有限责任公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118359610-A | MENIN-MLL interaction inhibitors | 生命医药有限责任公司 | 2024-07-19 | — | — | CN | disclosed |