Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25596266 | 0.92 | GABRD (0.51) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL30014379 | 0.92 | GABRD (0.51) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| Hydrochloric Acid SCHEMBL30864123 | 0.91 | GABRD (0.50) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL30014819 | 0.89 | HPGD (0.43) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL25920215 | 0.88 | MAPK1 (0.48) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL26100334 | 0.86 | NAMPT (0.41) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| Trifluoroacetic Acid SCHEMBL31161877 | 0.86 | GABRD (0.46) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL30392608 | 0.84 | HPGD (0.44) | HPGDKMT2APKMCRBN | |
| SCHEMBL25213849 | 0.83 | CHRM2 (0.41) | KMT2ACHRM2CHRM3 | |
| SCHEMBL28978062 | 0.83 | MGLL (0.39) | GABRDGABRA1GABRB1GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025159-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |