Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 17/20 | 1.00 |
| ▸ | PFKFB4 | Q16877 | 8/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21857359 | 1.00 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL21857521 | 0.89 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL21857159 | 0.87 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL21856940 | 0.87 | PFKFB3 (0.82) | PFKFB3PFKFB4 | |
| SCHEMBL21857339 | 0.87 | PFKFB3 (0.82) | PFKFB3PFKFB4 | |
| SCHEMBL21857057 | 0.87 | PFKFB4 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL21857478 | 0.86 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL21857007 | 0.85 | PFKFB3 (0.79) | PFKFB3PFKFB4 | |
| SCHEMBL794120 | 0.83 | PFKFB3 (0.71) | PFKFB3PFKFB4 | |
| SCHEMBL21857667 | 0.82 | PFKFB3 (0.74) | PFKFB3PFKFB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO PTE. LTD. (SG) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | PFKFB3, PFKFB4, PFKFB1 | PFKFB3 1/4885PFKFB4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.