Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Uric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | GDA | Q9Y2T3 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 6/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uric Acid SCHEMBL28407297 | 0.96 | MAPT (0.53) | MAPTADORA2BGDAACHEALDH1A1 | |
| Uric Acid SCHEMBL30885091 | 0.87 | MAPT (0.59) | MAPTADORA2BGDAACHEALDH1A1 | |
| SCHEMBL31152019 | 0.77 | MAPT (0.52) | MAPTADORA2BGDAACHEALDH1A1 | |
| SCHEMBL30728071 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEALDH1A1 | |
| SCHEMBL932949 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEALDH1A1 | |
| Uric Acid SCHEMBL2786719 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEALDH1A1 | |
| SCHEMBL30537976 | 0.74 | ALDH1A1 (0.60) | MAPTADORA2BGDAACHEALDH1A1 | |
| SCHEMBL932609 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEALDH1A1 | |
| SCHEMBL2837685 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEALDH1A1 | |
| SCHEMBL29737686 | 0.74 | MAPT (0.53) | MAPTADORA2BGDAACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115702507-A | Metal-free high voltage battery | 城市电力公司 | 2023-02-14 | — | — | CN | disclosed |