SCHEMBL2837685

SCHEMBL2837685

O=c1[nH]c(=O)c2[nH]c(Cl)nc2[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.53
ADORA2B P29275 2/20 0.49
GDA Q9Y2T3 2/20 0.44
ACHE P22303 1/20 0.44
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
XDH P47989 3/20 0.38
RPS6KA3 P51812 1/20 0.37
TYRO3 Q06418 1/20 0.37
DYRK1B Q9Y463 1/20 0.37
KDM4E B2RXH2 4/20 0.36
BLM P54132 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP1A2 P05177 2/20 0.36
PABPC1 P11940 1/20 0.36
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uric Acid SCHEMBL28407297 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
Uric Acid SCHEMBL30269772 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
SCHEMBL29737686 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
SCHEMBL932609 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
SCHEMBL447389 0.74 MAPT (0.84) MAPTADORA2BGDAACHEALDH1A1
SCHEMBL932949 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
SCHEMBL740931 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
Uric Acid SCHEMBL2786719 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
SCHEMBL30728071 0.74 MAPT (0.53) MAPTADORA2BGDAACHEALDH1A1
SCHEMBL30537976 0.74 ALDH1A1 (0.60) MAPTADORA2BGDAACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118584098-A Test strip for detecting uric acid and preparation method and application thereof 北京邦腾生物科技有限公司 2024-09-03 CN claimed
CN-118561845-A Hapten for uric acid content detection and application thereof 北京邦腾生物科技有限公司 2024-08-30 CN claimed
EP-3897677-A1 COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA ezCol B.V. (NL) 2021-10-27 EP claimed
US-20210275601-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT EZCOL B.V. (NL) 2021-09-09 US claimed
US-11026981-B2 LDL-cholesterol-lowering cell extract and food supplement EZCOL B.V. (NL) 2021-06-08 US claimed
WO-2020130813-A1 COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA EZCOL B.V. (NL) 2020-06-25 WO claimed
EP-3638272-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT ezCol B.V. (NL) 2020-04-22 EP claimed
US-20200101120-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT EZCOL B.V. (NL) 2020-04-02 US claimed
CN-110799202-A Cellular extracts and food supplements for lowering LDL-cholesterol 埃兹科尔公司 2020-02-14 CN claimed
WO-2018229223-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT EZCOL B.V. (NL) 2018-12-20 WO claimed
JP-10175853-A None JP disclosed
US-20250302885-A1 RHODOSPIRILLUM RUBRUM CELLS THAT LOWER PLASMA CHOLESTEROL WHILE LEAVING OTHER SERUM PROTEIN LEVELS UNAFFECTED Curador (BE) 2025-10-02 US disclosed
CN-116283867-B Aza-substituted xanthine or chloro xanthine derivatives and application thereof 山西农业大学 2025-07-25 CN disclosed
EP-4532496-A1 NOVEL PAR-2 INHIBITORS Domain Therapeutics (FR) 2025-04-09 EP disclosed
CN-118584098-A Test strip for detecting uric acid and preparation method and application thereof 北京邦腾生物科技有限公司 2024-09-03 CN disclosed
EP-0221996-B1 SUBSTITUTED 2,3-DIHYDRO-6-HYDROXY-PYRIMIDO [2,1-f] PURINE-4,8(1H,9H)-DIONES SCHERING CORPORATION (US) 1990-08-29 EP disclosed
US-4847377-A ANTIHYPERPROLIFERATIVE SKIN DISEASES SCHERING CORPORATION (US) 1989-07-11 US disclosed
US-4816458-A TOPICAL ADMINISTERING SCHERING CORPORATION (US) 1989-03-28 US disclosed
EP-0221996-A1 SUBSTITUTED 2,3-DIHYDRO-6-HYDROXY-PYRIMIDO [2,1-f] PURINE-4,8(1H,9H)-DIONES. SCHERING CORP (US) 1987-05-20 EP disclosed
WO-1986006724-A1 SUBSTITUTED 2,3-DIHYDRO-6-HYDROXY-PYRIMIDO AD2,1-f BD-PURINE-4,8(1H,9H)-DIONES SCHERING CORPORATION (US) 1986-11-20 WO disclosed