Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.44 |
| ▸ | SKP1 | P63208 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367933 | 0.86 | ITGA2B (0.63) | ACKR3CKS1BSKP1SKP2ITGA2B | |
| SCHEMBL368501 | 0.84 | ITGA2B (0.51) | CKS1BSKP1SKP2ITGA2BITGB3 | |
| SCHEMBL30270990 | 0.83 | RET (0.41) | ACKR3ITGA2BITGB3SMN1; SMN2RET | |
| SCHEMBL15130116 | 0.83 | ITGA2B (0.45) | ACKR3CKS1BSKP1SKP2ITGA2B | |
| SCHEMBL15137974 | 0.81 | SMARCA2 (0.44) | ACKR3CKS1BSKP1SKP2ITGA2B | |
| SCHEMBL15137944 | 0.80 | ALDH1A1 (0.44) | ACKR3CKS1BSKP1SKP2ITGA2B | |
| SCHEMBL359637 | 0.80 | ITGA2B (0.56) | CKS1BSKP1SKP2ITGA2BITGB3 | |
| SCHEMBL15137937 | 0.80 | ITGA2B (0.46) | ACKR3CKS1BSKP1SKP2ITGA2B | |
| SCHEMBL368819 | 0.80 | ITGA2B (0.55) | ACKR3ITGA2BLMNAMAPT | |
| SCHEMBL15130157 | 0.79 | ITGA2B (0.49) | ACKR3CKS1BSKP1SKP2ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416156-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | Remix Therapeutics Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064879-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| EP-4132936-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-02-15 | — | — | EP | disclosed |