Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30270968 | 0.83 | ACKR3 (0.49) | RETITGA2BITGB3ACKR3SMN1; SMN2 | |
| SCHEMBL30271032 | 0.79 | RET (0.37) | RETITGA2BSMN1; SMN2 | |
| SCHEMBL31396179 | 0.78 | RET (0.41) | RETJAK3NR1H2NR1H3 | |
| SCHEMBL31396262 | 0.74 | ALDH1A1 (0.42) | RETJAK3NR1H2NR1H3 | |
| SCHEMBL31267843 | 0.74 | RET (0.45) | RETJAK3SPRNR1H2NR1H3 | |
| SCHEMBL31396207 | 0.73 | RET (0.41) | RETJAK3SPRNR1H2NR1H3 | |
| SCHEMBL25074106 | 0.73 | JAK3 (0.40) | RETJAK3SPRNR1H2NR1H3 | |
| SCHEMBL24091519 | 0.71 | GPR119 (0.47) | RETJAK3NR1H2NR1H3 | |
| SCHEMBL31713482 | 0.71 | RET (0.52) | RETJAK3 | |
| SCHEMBL31713549 | 0.71 | RET (0.52) | RETJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416156-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | Remix Therapeutics Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064879-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| EP-4132936-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-02-15 | — | — | EP | disclosed |