SCHEMBL30272450

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	F2	P00734	4/20	0.46

▸	MC4R	P32245	1/20	0.45

▸	F2R	P25116	2/20	0.44

▸	OPRK1	P41145	6/20	0.42

▸	NMUR2	Q9GZQ4	1/20	0.41

▸	KISS1R	Q969F8	1/20	0.41

▸	CALCR	P30988	2/20	0.40

▸	CTSD	P07339	2/20	0.40

▸	CTSE	P14091	2/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30165153	0.96	MC4R (0.47)	F2MC4RF2ROPRK1NMUR2
SCHEMBL30258236	0.92	F2 (0.45)	F2MC4RF2ROPRK1CALCR
SCHEMBL30272526	0.90	F2 (0.58)	F2MC4ROPRK1NMUR2KISS1R
SCHEMBL30827588	0.89	MC4R (0.47)	F2MC4RF2RCALCRCTSD
SCHEMBL30827585	0.89	MC4R (0.46)	F2MC4RF2ROPRK1CTSD
SCHEMBL30272525	0.88	F2 (0.56)	F2MC4ROPRK1NMUR2KISS1R
SCHEMBL30272496	0.88	KDM1A (0.48)	F2MC4RNMUR2
SCHEMBL29590547	0.88	OPRK1 (0.46)	MC4RF2ROPRK1CTSD
SCHEMBL29630560	0.88	OPRK1 (0.46)	MC4RF2ROPRK1CTSD
SCHEMBL29958712	0.85	TRHR (0.41)	F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115746103-A	Preparation method of Bulevirtide	深圳市健翔生物制药有限公司	2023-03-07	—	—	CN	claimed
CN-115746104-A	Preparation method of Bulevirtide	深圳市健翔生物制药有限公司	2023-03-07	—	—	CN	disclosed
CN-115746103-A	Preparation method of Bulevirtide	深圳市健翔生物制药有限公司	2023-03-07	—	—	CN	disclosed