Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25036239 | 0.90 | DDB1 (0.46) | DDB1CRBN | |
| SCHEMBL23541145 | 0.85 | CDK7 (0.44) | DDB1CRBNCDK7CDK13CDK12 | |
| SCHEMBL31091736 | 0.80 | CRBN (0.53) | DDB1CRBN | |
| SCHEMBL30274014 | 0.79 | DDB1 (0.44) | DDB1CRBN | |
| SCHEMBL23540815 | 0.79 | DDB1 (0.53) | DDB1CRBN | |
| SCHEMBL31158014 | 0.78 | CRBN (0.50) | DDB1CRBN | |
| SCHEMBL24608454 | 0.75 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL29751074 | 0.75 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL26099316 | 0.75 | CRBN (0.44) | DDB1CRBN | |
| SCHEMBL31129610 | 0.75 | DDB1 (0.47) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |