Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 2/20 | 0.32 |
| ▸ | SKP1 | P63208 | 2/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | YAP1 | P46937 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29197010 | 0.92 | TLR9 (0.34) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL30273508 | 0.90 | CMKLR1 (0.36) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL29197711 | 0.85 | PRMT5 (0.38) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL24881049 | 0.80 | CCNT1 (0.38) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL30112443 | 0.80 | CCNT1 (0.38) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL23540770 | 0.78 | TLR9 (0.34) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL23541116 | 0.78 | NAMPT (0.41) | PRMT5GPR119 | |
| SCHEMBL30026597 | 0.78 | NAMPT (0.41) | PRMT5GPR119 | |
| SCHEMBL34461198 | 0.77 | YAP1 (0.41) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL31434068 | 0.77 | PRMT5 (0.37) | CCNT1CCNA2CDK2CDK9CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023019166-A1 | PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS | CALICO LIFE SCIENCES LLC (US) | 2023-02-16 | — | — | WO | disclosed |