SCHEMBL30274444

SCHEMBL30274444

O=C(O)CNC(=O)c1ncc2cc(Sc3ccccc3)ccc2c1O

nearest known ligand 0.77

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 18/20 0.77
EGLN2 Q96KS0 12/20 0.77
BBOX1 O75936 1/20 0.51
FTO Q9C0B1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522924 1.00 EGLN1 (0.77) EGLN1EGLN2BBOX1FTO
SCHEMBL522835 0.92 EGLN1 (0.66) EGLN1EGLN2BBOX1FTO
SCHEMBL522832 0.91 EGLN1 (0.64) EGLN1EGLN2
SCHEMBL522734 0.88 EGLN1 (0.61) EGLN1EGLN2BBOX1FTO
SCHEMBL15268851 0.87 EGLN2 (1.00) EGLN1EGLN2
SCHEMBL3914726 0.86 EGLN1 (0.59) EGLN1EGLN2BBOX1FTO
SCHEMBL15268873 0.86 EGLN2 (1.00) EGLN1EGLN2
SCHEMBL15270936 0.84 EGLN2 (1.00) EGLN1EGLN2
SCHEMBL523101 0.83 EGLN2 (0.71) EGLN1EGLN2FTO
SCHEMBL523031 0.83 EGLN1 (0.55) EGLN1EGLN2BBOX1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182424-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM FIBROGEN, INC. (US) 2024-06-06 US disclosed
EP-4142721-A1 HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS Bioage Labs, Inc. (US) 2023-03-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182424-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM EPOR, HAMP, TFRC EGLN1 24/4885EGLN2 9/4885BBOX1 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.