SCHEMBL30274485

SCHEMBL30274485

CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.52
▸ NMBR P28336 2/20 0.50
▸ GRPR P30550 2/20 0.50
▸ REN P00797 2/20 0.49
▸ F2 P00734 4/20 0.48
▸ RAMP1 O60894 1/20 0.47
▸ CALCRL Q16602 1/20 0.47
▸ OPRM1 P35372 1/20 0.47
▸ OPRD1 P41143 1/20 0.47
▸ CALCR P30988 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30274543 0.94 F2 (0.56) C5AR1NMBRGRPRF2OPRM1
SCHEMBL30785949 0.83 REN (0.52) RENF2
SCHEMBL31483294 0.83 SLC6A2 (0.60) RENRAMP1CALCRL
SCHEMBL31390815 0.81 SLC6A2 (0.56) RENCALCRLOPRM1OPRD1
SCHEMBL31670617 0.81 CALCR (0.55) C5AR1NMBRGRPRF2OPRD1
SCHEMBL29619755 0.81 LNPEP (0.63) C5AR1RENOPRM1
SCHEMBL30881954 0.80 F2 (0.48) C5AR1NMBRGRPRF2CALCRL
SCHEMBL4333867 0.80 C5AR1 (0.53) C5AR1RENF2OPRM1OPRD1
SCHEMBL30974080 0.80 F2 (0.46) C5AR1NMBRGRPRF2RAMP1
SCHEMBL4333862 0.80 C5AR1 (0.53) C5AR1RENF2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384540-B1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION KLISBIO S R L (IT) 2025-08-06 — — EP claimed
US-20250129123-A1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION SILK BIOMATERIALS S.R.L. (IT) 2025-04-24 — — US claimed
EP-4384540-A1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION Silk Biomaterials S.r.l. (IT) 2024-06-19 — — EP claimed
CN-117999277-A Bionic peptides and their use in bone regeneration 西尔克生物材料有限公司 2024-05-07 — — CN claimed
WO-2023016904-A1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION SILK BIOMATERIALS S.R.L. (IT) 2023-02-16 — — WO claimed
EP-4384540-B1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION KLISBIO S R L (IT) 2025-08-06 — — EP disclosed
US-20250129123-A1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION SILK BIOMATERIALS S.R.L. (IT) 2025-04-24 — — US disclosed
EP-4384540-A1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION Silk Biomaterials S.r.l. (IT) 2024-06-19 — — EP disclosed
CN-117999277-A Bionic peptides and their use in bone regeneration 西尔克生物材料有限公司 2024-05-07 — — CN disclosed
WO-2023016904-A1 BIOMIMETIC PEPTIDES AND THEIR USE IN BONE REGENERATION SILK BIOMATERIALS S.R.L. (IT) 2023-02-16 — — WO disclosed
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