Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | FER | P16591 | 1/20 | 0.54 |
| ▸ | LTK | P29376 | 1/20 | 0.54 |
| ▸ | CDK8 | P49336 | 1/20 | 0.54 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428940 | 1.00 | PARP1 (0.72) | PARP1PDGFRAFERLTKCDK8 | |
| SCHEMBL6543434 | 0.89 | PARP1 (0.58) | PARP1PDGFRAFERLTKCDK8 | |
| SCHEMBL30517066 | 0.87 | PARP1 (0.55) | PARP1PDGFRAFERLTKCDK8 | |
| Cyclohexanone SCHEMBL28964610 | 0.86 | PARP1 (0.55) | PARP1PDGFRAFERLTKCDK8 | |
| SCHEMBL2487811 | 0.84 | PARP1 (1.00) | PARP1NPSR1CES2ALDH1A1BCHE | |
| SCHEMBL57038 | 0.84 | PARP1 (1.00) | PARP1NPSR1CES2ALDH1A1BCHE | |
| SCHEMBL29038783 | 0.82 | PARP1 (0.95) | PARP1NPSR1CES2ALDH1A1BCHE | |
| SCHEMBL9413391 | 0.82 | PARP1 (0.95) | PARP1NPSR1CES2ALDH1A1BCHE | |
| SCHEMBL29157626 | 0.82 | PARP1 (0.95) | PARP1NPSR1CES2ALDH1A1BCHE | |
| SCHEMBL9681519 | 0.82 | PARP1 (0.95) | PARP1NPSR1CES2ALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1835 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165465-B1 | SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT | JOHNSON & JOHNSON VISION CARE (US) | 2026-02-18 | — | — | EP | claimed |
| US-12275743-B2 | Method for preparing near-infrared region II fluorescent small molecule | NANJING NUOYUAN MEDICAL INSTRUMENT CO.LTD (CN) | 2025-04-15 | — | — | US | claimed |
| CN-117843624-A | Near-infrared photothermal reagent based on coumarin and preparation method and application thereof | 吕梁学院 | 2024-04-09 | — | — | CN | claimed |
| US-20240077837-A1 | SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT | JOHNSON & JOHNSON VISION CARE (US) | 2024-03-07 | — | — | US | claimed |
| CN-115304539-B | Bromide heptamethine cyanine dye with near infrared two-region absorption and fluorescence emission, and preparation method and application thereof | 中国科学技术大学 | 2024-02-13 | — | — | CN | claimed |
| US-11672747-B2 | Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same | L'OREAL (FR) | 2023-06-13 | — | — | US | claimed |
| EP-4165465-A1 | SYSTEMS AND METHODS FOR INDICATING THE TIME ELAPSED SINCE THE OCCURRENCE OF A TRIGGERING EVENT | Johnson & Johnson Vision Care, Inc. (US) | 2023-04-19 | — | — | EP | claimed |
| CN-114790165-B | Synthesis method of near-infrared two-region fluorescent dye FD-1080 | 西安康福诺生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| WO-2023010925-A1 | METHOD FOR PREPARING SECOND NEAR-INFRARED REGION FLUORESCENT MICROMOLECULES | 南京诺源医疗器械有限公司 | 2023-02-09 | — | — | WO | claimed |
| CN-115521350-A | Near-infrared one-zone multifunctional fluorescent linker based on beta-lactase response, preparation method and application | 西安交通大学 | 2022-12-27 | — | — | CN | claimed |
| EP-0017621-B1 | DERIVATIVES OF NAPHTHOLACTAM, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | CIBA-GEIGY AG (CH) | 1982-12-15 | — | — | EP | claimed |
| US-4332937-A | DYES FOR POLYACRYLONITRILE | CIBA-GEIGY CORPORATION (US) | 1982-06-01 | — | — | US | claimed |
| US-4268668-A | FOR WOOL AND POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | claimed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | claimed |
| US-4246410-A | BENZINDOLE DYES OF YELLOW AND RED | CIBA -GEIGY AKTIENGESELLSCHAFT (CH) | 1981-01-20 | — | — | US | claimed |
| US-4152330-A | FROM 1-NAPHTHYL ISOCYANATE AND ANHYDROUS ALUMINUM HALIDE IN HOMOGENEOUS SOLUTION | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-01 | — | — | US | claimed |
| US-4116622-A | Dyeing preparations and process for dyeing polyacrylonitrile material in strong, neutral, clear blue shades | CIBA-GEIGY CORPORATION (US) | 1978-09-26 | — | — | US | claimed |
| US-4040779-A | Dry heat process to dyeing and printing organic material which can be dyed with cationic dyes | CIBA-GEIGY AG (CH) | 1977-08-09 | — | — | US | claimed |
| US-4003898-A | Process for the manufacture of cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-18 | — | — | US | claimed |
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275743-B2 | Method for preparing near-infrared region II fluorescent small molecule | GTF2I, SUB1, QTRT1 | PARP1 2554/4885PDGFRA 2297/4885FER 938/4885 |
| US-11672747-B2 | Process for dyeing keratin materials using a direct dye and an aliphatic ammonium salt, and composition comprising same | KRT18, MARK1, IK | PARP1 2651/4885PDGFRA 4265/4885FER 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.