Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027654 | 1.00 | NR1I2 (0.42) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL11342973 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TDP1HSD17B10ALOX15TSHR | |
| SCHEMBL16213944 | 0.83 | ALDH1A1 (0.39) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL26090841 | 0.81 | NR1I2 (0.41) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL18984963 | 0.80 | TSHR (0.40) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL18984962 | 0.80 | TSHR (0.40) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL8990247 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TDP1HSD17B10ALOX15LMNA | |
| SCHEMBL29040694 | 0.79 | GRIK1 (0.44) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL20214143 | 0.79 | L3MBTL1 (0.35) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL10943805 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TDP1HSD17B10ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198390-B2 | Self assembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2012-06-12 | — | — | US | disclosed |
| US-20100204415-A1 | SELFASSEMBLED GRAFTED POLYMERIC LAYER FOR USE IN BIOSENSOR TECHNOLOGY | IMEC (BE) | 2010-08-12 | — | — | US | disclosed |
| US-7728094-B2 | Selfassembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2010-06-01 | — | — | US | disclosed |
| US-20060252094-A1 | Selfassembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2006-11-09 | — | — | US | disclosed |
| US-5110914-A | Ion exchanging | UNIVERSITY OF MIAMI (US) | 1992-05-05 | — | — | US | disclosed |
| US-5086167-A | Ion exchanging with a ligand/matrix using a combination of pi-electron and electrostatic interaction of the ligand and ionic amino acids | UNIVERSITY OF MIAMI (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0371746-A2 | Method of separating proteins | UNIVERSITY OF MIAMI (US) | 1990-06-06 | — | — | EP | disclosed |