⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233140 | 0.93 | EEF2K (0.31) | — | |
| Hydrochloric Acid SCHEMBL7773582 | 0.91 | EEF2K (0.31) | — | |
| SCHEMBL31093227 | 0.81 | EEF2K (0.42) | — | |
| SCHEMBL31093239 | 0.81 | EEF2K (0.42) | — | |
| SCHEMBL24233211 | 0.79 | — | — | |
| SCHEMBL30277532 | 0.76 | P2RX7 (0.32) | — | |
| SCHEMBL7773581 | 0.76 | EEF2K (0.38) | — | |
| SCHEMBL24059182 | 0.75 | EEF2K (0.40) | — | |
| Hydrochloric Acid SCHEMBL7217608 | 0.75 | MEN1 (0.39) | — | |
| Iodide SCHEMBL7217073 | 0.74 | EEF2K (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| EP-4153747-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |
| EP-4153604-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-03-29 | — | — | EP | disclosed |