Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23844170 | 0.89 | NPC1 (0.76) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29244995 | 0.87 | NPC1 (0.66) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9338708 | 0.86 | NPC1 (0.62) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30277642 | 0.85 | NPC1 (0.62) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30277604 | 0.85 | SMN1; SMN2 (0.66) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22628664 | 0.85 | MEN1 (0.71) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL12218013 | 0.85 | RAB9A (0.70) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23844177 | 0.84 | FADS1 (0.62) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30277637 | 0.83 | NPC1 (0.59) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30277496 | 0.83 | RAB9A (0.64) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399198-A2 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | Taipei Medical University (TW) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023035005-A2 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | TAIPEI MEDICAL UNIVERSITY (TW) | 2023-03-09 | — | — | WO | disclosed |