Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30277673 | 0.93 | PTGES (0.42) | MRGPRX4MEN1KMT2APTGESALOX5 | |
| SCHEMBL30277679 | 0.93 | PTGES (0.49) | MRGPRX4MEN1KMT2APTGESALOX5 | |
| SCHEMBL30277552 | 0.92 | MAPT (0.42) | MRGPRX4KMT2APTGESALOX5PDK1 | |
| SCHEMBL30277647 | 0.88 | PTGES (0.48) | MEN1KMT2APTGESALOX5PDK1 | |
| SCHEMBL30277669 | 0.87 | PTGES (0.55) | MEN1KMT2APTGESALOX5PDK1 | |
| SCHEMBL30277491 | 0.86 | PTGES (0.47) | MEN1KMT2APTGESALOX5PDK1 | |
| SCHEMBL30277535 | 0.86 | PDK1 (0.52) | MEN1KMT2APTGESALOX5PDK1 | |
| SCHEMBL30277568 | 0.86 | PTGES (0.46) | MEN1KMT2APTGESALOX5PDK1 | |
| SCHEMBL30277596 | 0.86 | PTGES (0.46) | MEN1KMT2APTGESALOX5PDK1 | |
| SCHEMBL30277490 | 0.86 | PTGES (0.46) | MEN1KMT2APTGESALOX5PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399198-A2 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | Taipei Medical University (TW) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023035005-A2 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | TAIPEI MEDICAL UNIVERSITY (TW) | 2023-03-09 | — | — | WO | disclosed |