Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.50 |
| ▸ | PDE4A | P27815 | 7/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735735 | 1.00 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4CHTT | |
| SCHEMBL28868059 | 0.90 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CHTT | |
| SCHEMBL28868061 | 0.90 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CHTT | |
| SCHEMBL24735680 | 0.89 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4CHTT | |
| SCHEMBL29186623 | 0.85 | CYP3A4 (0.40) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL29186624 | 0.85 | CYP3A4 (0.40) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL30278221 | 0.83 | PDE4D (0.54) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL24735664 | 0.83 | PDE4D (0.54) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL28945888 | 0.82 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL348156 | 0.81 | LMNA (0.57) | HTTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258057-A1 | COMPOUNDS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-15 | — | — | WO | disclosed |