Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.54 |
| ▸ | PDE4A | P27815 | 9/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735664 | 1.00 | PDE4D (0.54) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| SCHEMBL28868070 | 0.90 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| SCHEMBL28868065 | 0.90 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| SCHEMBL29940033 | 0.89 | KDM4E (0.61) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| SCHEMBL24735855 | 0.89 | KDM4E (0.61) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| SCHEMBL24735678 | 0.89 | KDM4E (0.61) | PDE4DPDE4APDE4BPDE4CKDM4E | |
| SCHEMBL28945888 | 0.86 | PDE4D (0.53) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL24735741 | 0.84 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CJAK2 | |
| SCHEMBL24735740 | 0.84 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CJAK2 | |
| SCHEMBL30278269 | 0.84 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258057-A1 | COMPOUNDS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-15 | — | — | WO | disclosed |