Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.65 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865341 | 0.87 | HSP90AA1 (0.67) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL24735857 | 0.85 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL30278205 | 0.85 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL24736296 | 0.85 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL29800452 | 0.81 | PDE10A (0.54) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL27214159 | 0.81 | PDE10A (0.54) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2472343 | 0.79 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2227640 | 0.79 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2476277 | 0.77 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL4329054 | 0.77 | MAPT (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258057-A1 | COMPOUNDS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2022-12-15 | — | — | WO | disclosed |