Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.67 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.67 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CASP6 | P55212 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30278234 | 0.87 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL24735857 | 0.83 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL30278205 | 0.81 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL24736296 | 0.81 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2227640 | 0.80 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2476277 | 0.78 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL4329054 | 0.78 | MAPT (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| Benzoic Acid SCHEMBL4470216 | 0.78 | ALDH1A1 (0.54) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| Benzoic Acid SCHEMBL4470207 | 0.78 | ALDH1A1 (0.54) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL5442713 | 0.78 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856179-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| US-20240327410-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-03 | — | — | US | disclosed |
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-11993601-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV | 2024-05-28 | — | — | US | disclosed |
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | US | disclosed |
| US-11597728-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-07 | — | — | US | disclosed |
| US-20220315583-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-06 | — | — | US | disclosed |
| EP-3856179-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2021-08-04 | — | — | EP | disclosed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |
| US-7064117-B2 | Anti-cancer 2,3-dihydro-1H-pyrrolo[3,2-f]quinoline complexes of cobalt and chromium | AUCKLAND UNISERVICES LIMITED (NZ) | 2006-06-20 | — | — | US | disclosed |
| US-20050038249-A1 | Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium | AUCKLAND UNISERVICES LIMITED (NZ) | 2005-02-17 | — | — | US | disclosed |
| US-20040138195-A1 | Anti-cancer 2,3-dihydro-1h-pyrrolo[3,2-f[quinoline complexes of cobalt and chromium | AUCKLAND UNISERVICES LIMITED (NZ) | 2004-07-15 | — | — | US | disclosed |
| EP-1363908-A4 | ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO 3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM | AUCKLAND UNISERVICES LTD (NZ) | 2004-05-06 | — | — | EP | disclosed |
| EP-1363908-A1 | ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO 3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM | Auckland Uniservices Limited (NZ) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002059122-A1 | ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO[3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM | AUCKLAND UNISERVICES LIMITED (NZ) | 2002-08-01 | — | — | WO | disclosed |
| EP-0581500-B1 | Antibiotic carbapenem compounds | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5441949-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1995-08-15 | — | — | US | disclosed |
| EP-0581500-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138195-A1 | Anti-cancer 2,3-dihydro-1h-pyrrolo[3,2-f[quinoline complexes of cobalt and chromium | IDH1, HIF1AN, CA2 | HSP90AA1 3362/4885HSP90AB1 2815/4885PDE10A 3920/4885 |
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | HSP90AA1 2117/4885HSP90AB1 1909/4885PDE10A 794/4885 |
| US-11993601-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | HSP90AA1 2117/4885HSP90AB1 1909/4885PDE10A 794/4885 |
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | HSP90AA1 2117/4885HSP90AB1 1909/4885PDE10A 794/4885 |
| US-11597728-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | HSP90AA1 2117/4885HSP90AB1 1909/4885PDE10A 794/4885 |
| US-20240327410-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | HSP90AA1 2117/4885HSP90AB1 1909/4885PDE10A 794/4885 |
| US-20050038249-A1 | Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium | CA2, HIF1AN, PPOX | HSP90AA1 3153/4885HSP90AB1 2724/4885PDE10A 3559/4885 |
| US-20220315583-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | HSP90AA1 2117/4885HSP90AB1 1909/4885PDE10A 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.