Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 1.00 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | CASP6 | P55212 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329054 | 0.82 | MAPT (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2476277 | 0.82 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2472343 | 0.81 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL3557626 | 0.81 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL6634465 | 0.81 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL5865341 | 0.80 | HSP90AA1 (0.67) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL30278234 | 0.79 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL8488388 | 0.79 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL5442713 | 0.78 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL29984702 | 0.78 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265677-B1 | CORROSION DETECTION PRODUCT AND METHOD | BATTELLE MEMORIAL INSTITUTE (US) | 2019-05-15 | — | — | EP | claimed |
| EP-4631573-A2 | TEAD INHIBITORS | Orion Corporation (FI) | 2025-10-15 | — | — | EP | disclosed |
| EP-4323338-B1 | TEAD INHIBITORS | ORION CORP (FI) | 2025-10-08 | — | — | EP | disclosed |
| US-20240246908-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2024-07-25 | — | — | US | disclosed |
| US-10457662-B2 | Substituted amides for treating and preventing cancer | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-29 | — | — | US | disclosed |
| US-10457662-B2 | Substituted amides for treating and preventing cancer | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-10-29 | — | — | US | disclosed |
| US-20180282296-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CANCER | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2018-10-04 | — | — | US | disclosed |
| WO-2016187544-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CANCER | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-11-24 | — | — | WO | disclosed |
| US-20130053333-A1 | Aminoquinoline Derivatives | CONCERT PHARMACEUTICALS, INC. | 2013-02-28 | — | — | US | disclosed |
| US-20130053333-A1 | Aminoquinoline Derivatives | CONCERT PHARMACEUTICALS, INC. | 2013-02-28 | — | — | US | disclosed |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | METHYLGENE INC. (CA) | 2007-12-20 | — | — | US | disclosed |
| CN-1166636-C | Arylpiperazinyl-cyclohexylindole derivatives for the treatment of depression | — | 2004-09-15 | — | — | CN | disclosed |
| EP-1147083-B1 | ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION | WYETH CORP (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6465482-B2 | ANTIDEPRESSANTS; ANXIOLYTIC AGENTS; SEROTONIN-AFFECTED NERVOUS SYSTEM DISORDERS; ACTING AT THE 5-HT1A AUTORECEPTORS CONCOMMITANTLY WITH 5-HT TRANSPORTERS; ANTISEROTONIN AGENTS; SEROTONIN REUPTAKE INHIBITORS; HT3 RECEPTOR ANTAGONISTS | WYETH | 2002-10-15 | — | — | US | disclosed |
| US-20020045628-A1 | Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-04-18 | — | — | US | disclosed |
| CN-1336916-A | Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression | AMERICAN HOME PROD (US) | 2002-02-20 | — | — | CN | disclosed |
| US-6313126-B1 | FOR THRERAPY OF DISORDERS ASSOCIATED WITH DYSFUNCTION IN SEROTONERGIC NEUROTRANSMISSION, INCLUDING DEPRESSION AND ANXIETY | AMERICAN HOME PRODUCTS CORP | 2001-11-06 | — | — | US | disclosed |
| EP-1147083-A1 | ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000040554-A1 | ARYLPIPERAZINYL-CYCLOHEXYL INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282296-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING CANCER | NNT, NQO1, NAMPT | HSP90AA1 2976/4885HSP90AB1 2595/4885PDE10A 2569/4885 |
| US-20020045628-A1 | Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression | HTR2C, TPH1, TPH2 | HSP90AA1 4554/4885HSP90AB1 4500/4885PDE10A 1849/4885 |
| US-10457662-B2 | Substituted amides for treating and preventing cancer | NQO1, NNT, SIRT1 | HSP90AA1 2070/4885HSP90AB1 1900/4885PDE10A 3090/4885 |
| US-20240246908-A1 | TEAD INHIBITORS | TEAD3, TEAD1, TEAD2 | HSP90AA1 2926/4885HSP90AB1 2681/4885PDE10A 1750/4885 |
| US-20130053333-A1 | Aminoquinoline Derivatives | NQO2, QTRT2, RECQL | HSP90AA1 3873/4885HSP90AB1 3839/4885PDE10A 2096/4885 |
| US-20070293530-A1 | SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HAT1 | HSP90AA1 2256/4885HSP90AB1 1565/4885PDE10A 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.