Acrylic Acid

Acrylic Acid

SCHEMBL3027841

C=CC(=O)O.C=CC(=O)OCCCCCCCCCCCCCCCC(C)C

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.63
ALDH1A1 P00352 4/20 0.63
CYP3A4 P08684 2/20 0.63
HPGD P15428 1/20 0.53
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
HCAR2 Q8TDS4 3/20 0.44
THRB P10828 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
RARB P10826 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ESR1 P03372 1/20 0.37
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL1100290 1.00 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Acrylic Acid SCHEMBL2123019 1.00 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2778020 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1260225 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL35574 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25275202 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25228041 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25275191 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20503422 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL25270629 0.95 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100202992-A1 COMPOSITION CONTAINING A LIQUID FATTY PHASE GELLED WITH A SEMI-CRYSTALLINE COPOLYMER L'OREAL S.A. 2010-08-12 US disclosed
US-20090068133-A1 Composition containing a liquid fatty phase gelled with a semi-crystalline copolymer AIR PRODUCTS AND CHEMICALS, INC. 2009-03-12 US disclosed
EP-1833458-A1 COMPOSITION CONTAINING A LIQUID FATTY PHASE GELLED WITH A SEMI-CRYSTALLINE COPOLYMER L'OREAL, S.A. (FR) 2007-09-19 EP disclosed
WO-2005123011-A1 COMPOSITION CONTAINING A LIQUID FATTY PHASE GELLED WITH A SEMI-CRYSTALLINE COPOLYMER L'OREAL (FR) 2005-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100202992-A1 COMPOSITION CONTAINING A LIQUID FATTY PHASE GELLED WITH A SEMI-CRYSTALLINE COPOLYMER CUTA, FABP4, KRT18 TSHR 3636/4885ALDH1A1 3061/4885CYP3A4 2794/4885
US-20090068133-A1 Composition containing a liquid fatty phase gelled with a semi-crystalline copolymer CUTA, FABP4, KRT18 TSHR 3919/4885ALDH1A1 3583/4885CYP3A4 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.