Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25734257 | 1.00 | PKM (0.61) | PKMCYP19A1LMNAAKR1C3KMT2A | |
| SCHEMBL25072845 | 0.90 | PKM (0.63) | PKMCYP19A1LMNAAKR1C3KMT2A | |
| SCHEMBL30278517 | 0.90 | PKM (0.63) | PKMCYP19A1LMNAAKR1C3KMT2A | |
| SCHEMBL29221746 | 0.81 | KMT2A (0.46) | PKMCYP19A1LMNAKMT2AMEN1 | |
| SCHEMBL25073106 | 0.78 | MEN1 (0.59) | PKMAKR1C3KMT2AMEN1CYP3A4 | |
| SCHEMBL25072625 | 0.77 | KMT2A (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2834605 | 0.76 | PKM (0.79) | PKMCYP19A1LMNAAKR1C3KMT2A | |
| SCHEMBL5915342 | 0.76 | PDE4B (0.81) | PKMCYP19A1LMNAAKR1C3KMT2A | |
| SCHEMBL4013512 | 0.74 | KMT2A (0.55) | PKMLMNAAKR1C3KMT2AMEN1 | |
| SCHEMBL3061348 | 0.74 | PKM (0.84) | PKMLMNAAKR1C3PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387603-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | Enanta Pharmaceuticals, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-118103038-A | 17 Beta-hydroxysteroid dehydrogenase 13 inhibitors and methods of use thereof | 英安塔制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023023310-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2023-02-23 | — | — | WO | disclosed |