Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072879 | 1.00 | EPHX2 (0.36) | EPHX2IDO1TDO2PDE2APTPN1 | |
| SCHEMBL4400713 | 0.85 | EPHX2 (0.46) | EPHX2PDE2APTPN1 | |
| SCHEMBL16957535 | 0.81 | EPHX2 (0.36) | EPHX2IDO1TDO2PDE2AKCNN4 | |
| SCHEMBL28194011 | 0.81 | HRH4 (0.41) | EPHX2TRPA1 | |
| SCHEMBL29265561 | 0.77 | KCNJ1 (0.37) | TRPA1 | |
| SCHEMBL12436312 | 0.77 | AMY1A (0.37) | — | |
| SCHEMBL29376896 | 0.73 | EPAS1 (0.33) | EPHX2PTPN1 | |
| SCHEMBL26979442 | 0.73 | EPAS1 (0.33) | EPHX2PTPN1 | |
| SCHEMBL7931554 | 0.72 | EPAS1 (0.42) | EPHX2IDO1TDO2PDE2AKCNN4 | |
| SCHEMBL3935869 | 0.71 | ADRA2B (0.41) | EPHX2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387603-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | Enanta Pharmaceuticals, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-118103038-A | 17 Beta-hydroxysteroid dehydrogenase 13 inhibitors and methods of use thereof | 英安塔制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023023310-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2023-02-23 | — | — | WO | disclosed |