Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072917 | 1.00 | PTPN1 (0.41) | PTPN1PTPN6CDC25ATBK1CYP11B1 | |
| SCHEMBL30278463 | 0.74 | SLC6A4 (0.38) | TBK1CYP2A6CYP2C8MOGAT2KDM5B | |
| SCHEMBL19264733 | 0.74 | MALT1 (0.36) | CYP2C8MOGAT2PSMB5 | |
| SCHEMBL3078815 | 0.74 | IDO1 (0.39) | TBK1CYP2C8MOGAT2KDM4EMEN1 | |
| SCHEMBL31263364 | 0.74 | IDO1 (0.39) | TBK1CYP2C8MOGAT2KDM4EMEN1 | |
| SCHEMBL5210190 | 0.72 | CA12 (0.39) | TBK1CYP2C8MOGAT2KDM4EMEN1 | |
| SCHEMBL16152677 | 0.72 | CYP2C8 (0.36) | TBK1CYP2C8MOGAT2KDM5B | |
| SCHEMBL1567626 | 0.72 | SIGMAR1 (0.43) | TBK1CYP2C8MOGAT2HTR2CKDM5B | |
| SCHEMBL10707696 | 0.72 | CYP2C8 (0.36) | TBK1CYP2C8MOGAT2KDM5B | |
| SCHEMBL28081373 | 0.72 | QDPR (0.44) | TBK1CYP2C8MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387603-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | Enanta Pharmaceuticals, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-118103038-A | 17 Beta-hydroxysteroid dehydrogenase 13 inhibitors and methods of use thereof | 英安塔制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| WO-2023023310-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2023-02-23 | — | — | WO | disclosed |