SCHEMBL30278657

SCHEMBL30278657

O=C(O)C=Cc1ccc(Cl)cc1F

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.67
GPR183 P32249 1/20 0.51
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
MAPT P10636 4/20 0.49
ITGB2 P05107 2/20 0.49
ICAM1 P05362 2/20 0.49
ITGAL P20701 2/20 0.49
PTGER3 P43115 2/20 0.49
PTGER2 P43116 2/20 0.49
TBXA2R P21731 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414316 1.00 MIF (0.67) MIFGPR183HDAC3HDAC4HDAC1
SCHEMBL1233597 1.00 MIF (0.67) MIFGPR183HDAC3HDAC4HDAC1
SCHEMBL1233600 1.00 MIF (0.67) MIFGPR183HDAC3HDAC4HDAC1
SCHEMBL1674366 0.87 MIF (0.54) MIFGPR183MAPTITGB2ICAM1
SCHEMBL4925948 0.87 MIF (0.54) MIFGPR183MAPTITGB2ICAM1
SCHEMBL7828225 0.86 MIF (0.51) MIFGPR183HDAC3HDAC4HDAC1
SCHEMBL7828224 0.86 MIF (0.51) MIFGPR183HDAC3HDAC4HDAC1
SCHEMBL30310600 0.86 HDAC3 (0.50) MIFGPR183HDAC3HDAC4HDAC1
SCHEMBL22046677 0.86 HDAC3 (0.50) MIFGPR183HDAC3HDAC4HDAC1
SCHEMBL4608128 0.84 HDAC3 (0.49) MIFGPR183HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN claimed
CN-116003710-B Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2025-04-08 CN disclosed
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN disclosed